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Table 3 Volumetric characteristics of loco-regionally failed (LRF) vs loco-regionally controlled (LRC) patients without vs with late term reactions grade 3/4.

From: IMRT using simultaneously integrated boost (SIB) in head and neck cancer patients

 

LRF

LRC, G 0–2

LRC, G 3–4

n

21

77

14*

GTV PT (cc)

63

32

31.4

GTV LN (cc)

8.5

15

13

PTV1 (cc)

174

154

176

% PTV1 >110 %

0.8

0.8

1.3

% PTV1 < 95 %

13.5

8.3

8.0

  1. Gross tumor volume (GTV) in LRF patients was significantly larger than in controlled LRC individuals (p < 0.01). Isodose comparison showed PTV1 in controlled patients tendentially better covered, with less volumes getting doses < 95 %, compared with failed patients.
  2. * : the 2 patients with xerostomia grade 3 and the 3 patients with ulcers related to tumor persistence were excluded from this analysis.