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Table 3 Volumetric characteristics of loco-regionally failed (LRF) vs loco-regionally controlled (LRC) patients without vs with late term reactions grade 3/4.

From: IMRT using simultaneously integrated boost (SIB) in head and neck cancer patients

  LRF LRC, G 0–2 LRC, G 3–4
n 21 77 14*
GTV PT (cc) 63 32 31.4
GTV LN (cc) 8.5 15 13
PTV1 (cc) 174 154 176
% PTV1 >110 % 0.8 0.8 1.3
% PTV1 < 95 % 13.5 8.3 8.0
  1. Gross tumor volume (GTV) in LRF patients was significantly larger than in controlled LRC individuals (p < 0.01). Isodose comparison showed PTV1 in controlled patients tendentially better covered, with less volumes getting doses < 95 %, compared with failed patients.
  2. * : the 2 patients with xerostomia grade 3 and the 3 patients with ulcers related to tumor persistence were excluded from this analysis.