Figure 2
a, b, c: Shown is the surface of strict response additivity for the triple therapy 5 [Gy] + 0.001 [μg/ml] A + 1 [nM] B from three different perspectives. The axes are labeled with the dose/concentrations of the single agents (x1: A, x2: B, x3: XRT) in a right-handed cartesian coordinate system. The plot ranges are [0, 10] for XRT, [0, 0.1] for A and [0, 100] for B. The black dot marks the "point of therapy" namely (0.001|1|5); x1 = 0.001 and x2 = 1 means that the point is close to the x3-axis. The "point of therapy" lies in the middle of the plot range [0, 10].