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Table 1 Overview of dose-volume histograms with proton, IMRT and photon conventional planning for the PTV and OARs in the proton-photon planning comparison literature

From: Radiation therapy planning with photons and protons for early and advanced breast cancer: an overview

PTV/OARs Series (ref. no.) V95% Protons (mean) V95% IMRT (mean) V95% Photons (mean) Mean Dose (%) Protons Mean Dose (%) IMRT Mean Dose (%) Photons
PTV (breast only)       
Lomax et al. [33] 97.1 92.2 86.6    
Johansson et al. [34] 94.0 85.9 88.8    
Fogliata et al. [38] 99.8 95.5 92.2    
Heart       
Lomax et al. [33]     11.6 24.0 29.3
Johansson et al. [34]     21.0* 41.0* 61.0*
Fogliata et al. [38]     4.4 5.6 5.0
Lung (ipsilateral)       
Lomax et al. [33]     25.0 33.0 33.3
Johansson et al. [34]     1.0* 18.0* 29.0*
Fogliata et al. [38]     7.0 17.1 22.5
  1. IMRT, intensity modulated radiotherapy; PTV, planning target volume; OAR, organ at risk; V95%, volume (in percentage) receiving 95% of the prescribed dose.
  2. *estimated % of the prescribed dose from the dose-volume histograms administered to the heart and lung