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Table 1 Overview of dose-volume histograms with proton, IMRT and photon conventional planning for the PTV and OARs in the proton-photon planning comparison literature

From: Radiation therapy planning with photons and protons for early and advanced breast cancer: an overview

PTV/OARs Series (ref. no.)

V95% Protons (mean)

V95% IMRT (mean)

V95% Photons (mean)

Mean Dose (%) Protons

Mean Dose (%) IMRT

Mean Dose (%) Photons

PTV (breast only)

      

Lomax et al. [33]

97.1

92.2

86.6

   

Johansson et al. [34]

94.0

85.9

88.8

   

Fogliata et al. [38]

99.8

95.5

92.2

   

Heart

      

Lomax et al. [33]

   

11.6

24.0

29.3

Johansson et al. [34]

   

21.0*

41.0*

61.0*

Fogliata et al. [38]

   

4.4

5.6

5.0

Lung (ipsilateral)

      

Lomax et al. [33]

   

25.0

33.0

33.3

Johansson et al. [34]

   

1.0*

18.0*

29.0*

Fogliata et al. [38]

   

7.0

17.1

22.5

  1. IMRT, intensity modulated radiotherapy; PTV, planning target volume; OAR, organ at risk; V95%, volume (in percentage) receiving 95% of the prescribed dose.
  2. *estimated % of the prescribed dose from the dose-volume histograms administered to the heart and lung