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Table 3 Incidence of thromboembolic toxicity in recent retrospective cohorts using cisplatin

From: Cisplatin chemotherapy (without erythropoietin) and risk of life-threatening thromboembolic events in carcinoma of the uterine cervix: the tip of the iceberg? A review of the literature

Trial

Chemotherapy

XRT

Toxicity

No. CTX Pts

Jacobsen et al [9] (cervix)

Cis 40 mg/m2 q wk X 6 concurrent

85 Gy to pt A

1 Grade 5

3 Grade 4 CVT

48

Mallincrodt (unpublished) (cervix)

Cis 40 mg/m2 q wk X 6 concurrent

85 Gy to pt A

1 Grade 5

1 Grade 4

80

  1. NOS = Not otherwise specified CVT = Cardiovascular Toxicity SBP: Small Bowel Perforation Cis = Cisplatin 5FU = 5 Fluorouracil WP = Whole Pelvis Gy = Gray
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Radiation Oncology

ISSN: 1748-717X

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