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Table 4 Normal tissue avoidance for the IMRT and CRT plans in 12 patients, Ratio relative to a 4FB technique

From: Dosimetric comparison of intensity-modulated, conformal, and four-field pelvic radiotherapy boost plans for gynecologic cancer: a retrospective planning study

Technique

OAR

Median VL (Range)

Median VI (Range)

Median VH (Range)

Median VHDT (Range)

Median VH+VHDT (Range)

IMRT – 6 field

Rectum

2.6 (1.1–168)

1.2 (0.4–16.4)

0.7 (0.4–1.5)

2.1 (0–134)

0.781,2 (0.48–0.98)

 

Bladder

10.7 (1.6–314)

1.0 (0.4–5.1)

0.7 (0.5–0.9)

2.9 (1.0–569)

0.811,2 (0.65–0.98)

IMRT – 8 field

Rectum

1.8 (0.1–166)

1.1 (0.6–9.5)

0.9 (0.6–1.5)

0.9 (0.1–208)

0.901,2 (0.61–1.06)

 

Bladder

7.1 (1.7–490)

1.0 (0.6–8.5)

0.8 (0.6–0.9)

0.8 (0–17)

0.781,2 (0.67–0.88)

CRT

Rectum

1.1 (0–71)

1.0 (0.4–12)

1.0 (0.3–1.3)

1.0 (0–1.8)

1.02 (0.61–1.3)

 

Bladder

7.8 (1.9–336)

0.55 (0.3–0.9)

0.87 (0.4–1.4)

1.1 (0–403)

0.96 (0.85–1.4)

  1. (1) IMRT vs. 4FB, p ≤ 0.001 by t-test
  2. (2) IMRT vs. CRT, p ≤ 0.05
  3. (CRT) Conformal radiotherapy
  4. (IMRT) Intensity-modulated radiotherapy
  5. (4FB) Four field box technique
  6. (VL)Volume of tissue receiving ≤ 33% of the prescription dose
  7. (VI)Volume of tissue receiving 34–66% of the prescription dose
  8. (VH)Volume of tissue receiving 67–100% of the prescription dose
  9. (VHDT)Volume of tissue receiving >100% of the prescription dose (V100%)
  10. (VH+VHDT)Volume of tissue receiving >66% of the prescribed dose (V66%)