TY - JOUR AU - Licitra, L. AU - Locati, L. D. AU - Bossi, P. PY - 2004 DA - 2004// TI - Head and neck cancer JO - Ann Oncol VL - 15 ID - Licitra2004 ER - TY - JOUR AU - Arteaga, C. PY - 2003 DA - 2003// TI - Targeting HER1/EGFR: a molecular approach to cancer therapy JO - Semin Oncol VL - 30 UR - https://doi.org/10.1016/S0093-7754(03)70010-4 DO - 10.1016/S0093-7754(03)70010-4 ID - Arteaga2003 ER - TY - JOUR AU - Baselga, J. PY - 2001 DA - 2001// TI - Targeting the epidermal growth factor receptor: a clinical reality JO - J Clin Oncol VL - 19 ID - Baselga2001 ER - TY - JOUR AU - Bonner, J. A. AU - Harari, P. M. AU - Giralt, J. AU - Azarnia, N. AU - Shin, D. M. AU - Cohen, R. B. AU - Jones, C. U. AU - Sur, R. AU - Raben, D. AU - Jassem, J. AU - Ove, R. AU - Kies, M. S. AU - Baselga, J. AU - Youssoufian, H. AU - Amellal, N. AU - Rowinsky, E. K. AU - Ang, K. K. PY - 2006 DA - 2006// TI - Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck JO - N Engl J Med VL - 354 UR - https://doi.org/10.1056/NEJMoa053422 DO - 10.1056/NEJMoa053422 ID - Bonner2006 ER - TY - JOUR AU - Cohen, S. AU - Carpenter, G. AU - King, L. PY - 1980 DA - 1980// TI - Epidermal growth factor-receptor-protein kinase interactions: co-purification of receptor and epidermal growth factor-enhanced phosphorylation activity JO - J Biol Chem VL - 255 ID - Cohen1980 ER - TY - JOUR AU - Cohen, S. PY - 1965 DA - 1965// TI - The stimulation of epidermal proliferation by a specific protein (EGF) JO - Dev Biol VL - 12 UR - https://doi.org/10.1016/0012-1606(65)90005-9 DO - 10.1016/0012-1606(65)90005-9 ID - Cohen1965 ER - TY - JOUR AU - Davies, R. L. AU - Grosse, V. A. AU - Kucherlapati, R. AU - Bothwell, M. PY - 1980 DA - 1980// TI - Genetic analysis of epidermal growth factor action: assignment of human epidermal growth factor receptor gene to chromosome 7 JO - Proc Natl Acad Sci VL - 77 UR - https://doi.org/10.1073/pnas.77.7.4188 DO - 10.1073/pnas.77.7.4188 ID - Davies1980 ER - TY - JOUR AU - Roskoski, R. PY - 2004 DA - 2004// TI - The ErbB/HER receptor protein-tyrosine kinases and cancer JO - Biochem Biophys Res Commun VL - 319 UR - https://doi.org/10.1016/j.bbrc.2004.04.150 DO - 10.1016/j.bbrc.2004.04.150 ID - Roskoski2004 ER - TY - JOUR AU - Schmidt-Ullrich, R. K. AU - Valerie, K. C. AU - Chan, W. AU - McWilliams, D. PY - 1994 DA - 1994// TI - Altered expression of epidermal growth factor receptor and extrogen receptor in MCF-7 cells after single and repeated radiation exposures JO - Int J Radiat Oncol Biol Phys VL - 29 UR - https://doi.org/10.1016/0360-3016(94)90570-3 DO - 10.1016/0360-3016(94)90570-3 ID - Schmidt-Ullrich1994 ER - TY - JOUR AU - Dent, P. AU - Reardon, D. B. AU - Park, J. S. AU - Bowers, G. AU - Logsdon, C. AU - Valerie, K. AU - Schmidt-Ullrich, R. PY - 1999 DA - 1999// TI - Radiation-induced release of transforming growth factor α activates the epidermal growth factor receptor and mitogen-activated protein kinase pathway in carcinoma cells, leading to increased proliferation and protection from radiation-induced cell death JO - Mol Biol Cell VL - 10 UR - https://doi.org/10.1091/mbc.10.8.2493 DO - 10.1091/mbc.10.8.2493 ID - Dent1999 ER - TY - JOUR AU - Tofilon, P. J. AU - Saxman, S. AU - Coleman, C. N. PY - 2003 DA - 2003// TI - Molecular targets for radiation therapy: bringing preclinical data into clinical trials JO - Clin Cancer Res VL - 9 ID - Tofilon2003 ER - TY - JOUR AU - Sartor, C. PY - 2004 DA - 2004// TI - Mechanisms of Disease: radiosensitization by epidermal growth factor receptor inhibitors JO - Nat Clin Pract Oncol VL - 1 UR - https://doi.org/10.1038/ncponc0048 DO - 10.1038/ncponc0048 ID - Sartor2004 ER - TY - JOUR AU - Carpenter, G. AU - Cohen, S. PY - 1979 DA - 1979// TI - Epidermal growth factor JO - Annu Rev Biochem VL - 48 UR - https://doi.org/10.1146/annurev.bi.48.070179.001205 DO - 10.1146/annurev.bi.48.070179.001205 ID - Carpenter1979 ER - TY - JOUR AU - Grandis, J. AU - Tweardy, D. PY - 1993 DA - 1993// TI - Elevated levels of transforming growth factor α and epidermal growth factor receptor messenger RNA are early markers of carcinogenesis in head and neck cancer JO - Cancer Res VL - 53 ID - Grandis1993 ER - TY - JOUR AU - Grandis, J. R. AU - Chakraborty, A. AU - Zeng, Q. AU - Melhem, M. F. AU - Tweardy, D. J. PY - 1998 DA - 1998// TI - Downregulation of TGF-alpha protein expression with antisense oligonucleotides inhibits proliferation of head and neck squamous carcinoma but not normal mucosal epithelial cells JO - J Cell Biochem VL - 69 UR - https://doi.org/3.0.CO;2-U DO - 3.0.CO;2-U ID - Grandis1998 ER - TY - JOUR AU - Rubin Grandis, J. AU - Melhem, M. F. AU - Barnes, E. L. AU - Tweardy, D. J. PY - 1996 DA - 1996// TI - Quantitative immunohistochemical analysis of transforming growth factor α and epidermal growth factor receptor in patients with squamous cell carcinoma of the head and neck JO - Cancer VL - 78 UR - https://doi.org/3.0.CO;2-X DO - 3.0.CO;2-X ID - Rubin Grandis1996 ER - TY - JOUR AU - Baumann, M. AU - Krause, M. PY - 2004 DA - 2004// TI - Targeting the epidermal growth factor receptor in radiotherapy: radiobiological mechanisms, preclinical and clinical results JO - Radiother Oncol VL - 72 UR - https://doi.org/10.1016/j.radonc.2004.07.007 DO - 10.1016/j.radonc.2004.07.007 ID - Baumann2004 ER - TY - JOUR AU - Maurizi, M. AU - Almadori, G. AU - Ferrandina, G. AU - Ferrandina, G. AU - Distefano, M. AU - Romanini, M. E. AU - Cadoni, G. AU - Benedetti-Panici, P. AU - Paludetti, G. AU - Scambia, G. AU - Mancuso, S. PY - 1996 DA - 1996// TI - Prognostic significance of epidermal growth factor receptor in laryngeal squamous cell carcinoma JO - Br J Cancer VL - 74 UR - https://doi.org/10.1038/bjc.1996.525 DO - 10.1038/bjc.1996.525 ID - Maurizi1996 ER - TY - STD TI - Demiral AN, Sarioglu S, Birlik B, Sen M, Kinay M: Prognostic significance of EGF receptor expression in early glottic cancer.Auris Nasus Larynx31: 417-424. 10.1016/j.anl.2004.05.003 ID - ref19 ER - TY - JOUR AU - Ang, K. K. AU - Berkey, B. A. AU - Tu, X. AU - Zhang, H. Z. AU - Katz, R. AU - Hammond, E. H. AU - Fu, K. K. AU - Milas, L. PY - 2002 DA - 2002// TI - Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma JO - Cancer Res VL - 62 ID - Ang2002 ER - TY - JOUR AU - Albanell, J. AU - Codony-Servat, J. AU - Rojo, F. AU - Del Camp, J. M. AU - Sauleda, S. AU - Anido, J. AU - Raspall, G. AU - Giralt, J. AU - Rosello, J. AU - Nicholson, R. I. AU - Mendelsohn, J. AU - Baselga, J. PY - 2001 DA - 2001// TI - Activated extracellular signal-regulated kinases: association with epidermal growth factor receptor/transforming growth factor alpha expression in head and neck squamous carcinoma and inhibition by anti-epidermal growth factor receptor treatments JO - Cancer Res VL - 61 ID - Albanell2001 ER - TY - JOUR AU - Hambek, M. AU - Baghi, M. AU - Baumaun, H. AU - Strebhard, K. AU - Adunka, O. AU - Gstottner, W. AU - Knecht, R. PY - 2005 DA - 2005// TI - Iressa (ZD 1839) inhibits phosphorylation of three different downstream signal transducers in head and neck cancer (SCCHN) JO - Anticancer Res VL - 25 ID - Hambek2005 ER - TY - JOUR AU - Raben, D. AU - Bianco, C. AU - Milas, L. AU - Ang, K. K. PY - 2004 DA - 2004// TI - Targeted therapies and radiation for the treatment of head and neck cancer: are we making progress? JO - Semin Radiat Oncol VL - 14 UR - https://doi.org/10.1053/j.semradonc.2003.12.009 DO - 10.1053/j.semradonc.2003.12.009 ID - Raben2004 ER - TY - JOUR AU - Burtness, B. A. AU - Li, Y. AU - Flood, W. AU - Mattar, B. I. AU - Forastiere, A. A. PY - 2002 DA - 2002// TI - Phase III trial comparing cisplatin (C) + placebo (P) + anti-epidermal growth factor antibody (EGF-R) C225 in patients (pts) with metastatic/recurrent head and neck cancer (HNC) JO - Proc Am Soc Clin Oncol VL - 21 ID - Burtness2002 ER - TY - JOUR AU - Bonner, J. A. AU - Raisch, K. P. AU - Trummell, H. Q. AU - Robert, F. AU - Meredith, R. B. AU - Spencer, S. A. AU - Buschbaum, D. J. AU - Saleh, M. N. AU - Stackhouse, M. A. AU - LoBuglio, A. F. AU - Peters, G. E. AU - Carroll, W. R. AU - Waksal, H. W. PY - 2000 DA - 2000// TI - Enhanced apoptosis with combination C225/radiation treatment serves as the impetus for clinical investigation in head and neck cancers JO - J Clin Oncol VL - 18 ID - Bonner2000 ER - TY - JOUR AU - Harari, P. M. AU - Huang, S. PY - 2006 DA - 2006// TI - Radiation combined with EGFR Signal Inhibitors JO - Semin Radiat Oncol VL - 16 UR - https://doi.org/10.1016/j.semradonc.2005.08.005 DO - 10.1016/j.semradonc.2005.08.005 ID - Harari2006 ER - TY - JOUR AU - Solomon, B. AU - Hagekyriakou, J. AU - Trivett, M. AU - Stacker, S. AU - McArthur, G. AU - Cullinane, C. PY - 2003 DA - 2003// TI - EGFR blockade with ZD1839 ("Iressa") potentiates the antitumor effects of single and multiple fractions of ionizing radiation in human A431 squamous cell carcinoma JO - Int J Radiat Oncol Biol Phys VL - 55 UR - https://doi.org/10.1016/S0360-3016(02)04357-2 DO - 10.1016/S0360-3016(02)04357-2 ID - Solomon2003 ER - TY - JOUR AU - Cohen, E. E. AU - Haraf, D. J. AU - Stenson, K. M. AU - Blair, E. AU - Brockstein, B. E. AU - Mauer, A. M. AU - Dekker, A. AU - Williams, R. AU - Lester, E. AU - Vokes, E. E. PY - 2005 DA - 2005// TI - Integration of gefitinib (G) into a chemoradiation (CRT) regimen, followed by G adjuvant therapy in patients with locally advanced head and neck cancer (HNC): a phase II trial JO - J Clin Oncol VL - 23 ID - Cohen2005 ER - TY - JOUR AU - Overgaard, J. AU - Hansen, H. S. AU - Specht, L. AU - Overgaard, M. AU - Grau, C. AU - Andersen, E. AU - Bentzen, J. AU - Basholt, L. AU - Hansen, O. AU - Johansen, J. AU - Andersen, L. AU - Evensen, J. F. PY - 2003 DA - 2003// TI - Five compared with six fractions per week of conventional radiotherapy of squmous-cell carcinoma of head and neck: DAHANCA 6 and 7 randomised controlled trial JO - Lancet VL - 362 UR - https://doi.org/10.1016/S0140-6736(03)14361-9 DO - 10.1016/S0140-6736(03)14361-9 ID - Overgaard2003 ER - TY - JOUR AU - Pignon, J. P. AU - Bourhis, J. AU - Domenge, C. AU - Designe, L. PY - 2000 DA - 2000// TI - Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data JO - Lancet VL - 355 UR - https://doi.org/10.1016/S0140-6736(00)90011-4 DO - 10.1016/S0140-6736(00)90011-4 ID - Pignon2000 ER - TY - JOUR AU - Budach, W. AU - Hehr, T. AU - Budach, V. AU - Belka, C. AU - Dietz, K. PY - 2006 DA - 2006// TI - A meta-analysis of hyperfractionated and accelerated radiotherapy and combined therapy and radiotheapy regimens in unresected locally advanced squamous cell carcinoma of the head and neck JO - BMC Cancer VL - 6 UR - https://doi.org/10.1186/1471-2407-6-28 DO - 10.1186/1471-2407-6-28 ID - Budach2006 ER - TY - JOUR AU - Gorski, D. H. AU - Beckett, M. A. AU - Jasnowiak, N. T. AU - Calvin, D. P. AU - Mauceri, H. J. AU - Salloum, R. M. AU - Seetharam, S. AU - Koons, A. AU - Hari, D. M. AU - Kufe, D. W. AU - Weichselbaum, R. R. PY - 1999 DA - 1999// TI - Blockade of the vascular endothelial growth factor stress response increases the the antitumor effects of ionizing radiation JO - Cancer Res VL - 59 ID - Gorski1999 ER - TY - JOUR AU - Sonveaux, P. AU - Brouet, A. AU - Havaux, X. AU - Gregoire, V. AU - Dessy, C. AU - Balligand, J. L. AU - Feron, O. PY - 2003 DA - 2003// TI - Irradiation-induced angiogenesis through the up-regulation of the nitric oxide pathway: implications for tumor radiotherapy JO - Cancer Res VL - 63 ID - Sonveaux2003 ER -