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  1. Research

    Whole breast and regional nodal irradiation in prone versus supine position in left sided breast cancer

    Prone whole breast irradiation (WBI) leads to reduced heart and lung doses in breast cancer patients receiving adjuvant radiotherapy. In this feasibility trial, we investigated the prone position for whole bre...

    Pieter Deseyne, Bruno Speleers, Wilfried De Neve, Bert Boute, Leen Paelinck, Tom Van Hoof, Joris Van de Velde, Annick Van Greveling, Chris Monten, Giselle Post, Herman Depypere and Liv Veldeman

    Radiation Oncology 2017 12:89

    Published on: 26 May 2017

  2. Research

    Seven fractions to deliver partial breast irradiation: the toxicity is Low

    To assess toxicity and clinical outcome, in breast cancer patients treated with external beam partial breast irradiation (PBI) consisting of 35 Gy in 7 daily fractions (5 Gy/fraction).

    Marco Trovo, Michele Avanzo, Lorenzo Vinante, Carlo Furlan, Francesco Fiorica, Tiziana Perin, Loredana Militello, Simon Spazzapan, Massimiliano Berretta, Rajesh Jena, Joseph Stancanello, Erica Piccoli, Mario Mileto, Elvia Micheli, Mario Roncadin and Samuele Massarut

    Radiation Oncology 2017 12:86

    Published on: 23 May 2017

  3. Research

    Is it possible for knowledge-based planning to improve intensity modulated radiation therapy plan quality for planners with different planning experiences in left-sided breast cancer patients?

    Knowledge-based planning (KBP) is a promising technique that can improve plan quality and increase planning efficiency. However, no attempts have been made to extend the domain of KBP for planners with differe...

    Juanqi Wang, Weigang Hu, Zhaozhi Yang, Xiaohui Chen, Zhiqiang Wu, Xiaoli Yu, Xiaomao Guo, Saiquan Lu, Kaixuan Li and Gongyi Yu

    Radiation Oncology 2017 12:85

    Published on: 22 May 2017

  4. Review

    Diagnostic and treatment modalities for patients with cervical lymph node metastases of unknown primary site – current status and challenges

    This review aims to provide a comprehensive overview of the literature and elucidate open questions for future clinical trials concerning diagnostics and treatment modalities for cervical cancer of unknown pri...

    Jens Müller von der Grün, Aykut Tahtali, Shahram Ghanaati, Claus Rödel and Panagiotis Balermpas

    Radiation Oncology 2017 12:82

    Published on: 10 May 2017

  5. Research

    Clinical implementation of a knowledge based planning tool for prostate VMAT

    A knowledge based planning tool has been developed and implemented for prostate VMAT radiotherapy plans providing a target average rectum dose value based on previously achievable values for similar rectum/PTV...

    Richard Powis, Andrew Bird, Matthew Brennan, Susan Hinks, Hannah Newman, Katie Reed, John Sage and Gareth Webster

    Radiation Oncology 2017 12:81

    Published on: 8 May 2017

  6. Research

    A comprehensive dosimetric study on switching from a Type-B to a Type-C dose algorithm for modern lung SBRT

    Type-C dose algorithms provide more accurate dosimetry for lung SBRT treatment planning. However, because current dosimetric protocols were developed based on conventional algorithms, its applicability for the...

    Christina Zhou, Nathan Bennion, Rongtao Ma, Xiaoying Liang, Shuo Wang, Kristina Zvolanek, Megan Hyun, Xiaobo Li, Sumin Zhou, Weining Zhen, Chi Lin, Andrew Wahl and Dandan Zheng

    Radiation Oncology 2017 12:80

    Published on: 5 May 2017

  7. Research

    Does age really matter? Radiotherapy in elderly patients with glioblastoma, the Munich experience

    Glioblastoma is usually diagnosed around the age of 60–70 years. Patients older than 65 years are frequently described as “elderly”. Several trials with monotherapy have established treatment regimens that off...

    Christoph Straube, Hagen Scherb, Jens Gempt, Stefanie Bette, Claus Zimmer, Friederike Schmidt-Graf, Jürgen Schlegel, Bernhard Meyer and Stephanie E. Combs

    Radiation Oncology 2017 12:77

    Published on: 28 April 2017

  8. Research

    Dose tracking assessment for image-guided radiotherapy of the prostate bed and the impact on clinical workflow

    The cumulative dose was compared with the planned dose among fourteen patients undergoing image-guided, intensity-modulated radiotherapy of the prostate bed. Moreover, we investigated the feasibility of adding...

    Lucia Clara Orlandini, Marianna Coppola, Christian Fulcheri, Luna Cernusco, Pei Wang and Luca Cionini

    Radiation Oncology 2017 12:78

    Published on: 28 April 2017

  9. Research

    Setup errors in patients with head-neck cancer (HNC), treated using the Intensity Modulated Radiation Therapy (IMRT) technique: how it influences the customised immobilisation systems, patient’s pain and anxiety

    In patients with head-neck cancer treated with IMRT, immobility of the upper part of the body during radiation is maintained by means of customised immobilisation devices.

    Massimiliano Contesini, Monica Guberti, Roberta Saccani, Luca Braglia, Cinzia Iotti, Andrea Botti, Emilio Abbati and Marina Iemmi

    Radiation Oncology 2017 12:72

    Published on: 27 April 2017

  10. Research

    Dosimetric comparison of helical tomotherapy, VMAT, fixed-field IMRT and 3D-conformal radiotherapy for stage I-II nasal natural killer T-cell lymphoma

    The aim of this study was to compare radiotherapy plans for Stage I-II nasal natural killer/T-cell lymphoma (NNKTL) using helical tomotherapy (HT), volumetric-modulated arc therapy (VMAT), Fixed-Field intensit...

    Xianfeng Liu, Erliang Huang, Ying Wang, Yanan He, Huanli Luo, Mingsong Zhong, Da Qiu, Chao Li, Han Yang, Guanglei He, Juan Zhou and Fu Jin

    Radiation Oncology 2017 12:76

    Published on: 27 April 2017

  11. Research

    RapidPlan head and neck model: the objectives and possible clinical benefit

    To evaluate a knowledge based planning model for RapidPlan (RP) generated for advanced head and neck cancer (HNC) patient treatments, as well its ability to possibly improve the clinical plan quality. The stab...

    A. Fogliata, G. Reggiori, A. Stravato, F. Lobefalo, C. Franzese, D. Franceschini, S. Tomatis, P. Mancosu, M. Scorsetti and L. Cozzi

    Radiation Oncology 2017 12:73

    Published on: 27 April 2017

  12. Research

    A short time interval between radiotherapy and hyperthermia reduces in-field recurrence and mortality in women with advanced cervical cancer

    Combined radiotherapy and hyperthermia is a well-established alternative to chemoradiotherapy for advanced stage cervical cancer patients with a contraindication for chemotherapy. Pre-clinical evidence suggest...

    Caspar M. van Leeuwen, Arlene L. Oei, Kenneth W. T. K. Chin, Johannes Crezee, Arjan Bel, Anneke M. Westermann, Marrije R. Buist, Nicolaas A. P. Franken, Lukas J. A. Stalpers and H. Petra Kok

    Radiation Oncology 2017 12:75

    Published on: 27 April 2017

  13. Research

    Predicting liver SBRT eligibility and plan quality for VMAT and 4π plans

    It is useful to predict planned dosimetry and determine the eligibility of a liver cancer patient for SBRT treatment using knowledge based planning (KBP). We compare the predictive accuracy using the overlap v...

    Angelia Tran, Kaley Woods, Dan Nguyen, Victoria Y. Yu, Tianye Niu, Minsong Cao, Percy Lee and Ke Sheng

    Radiation Oncology 2017 12:70

    Published on: 24 April 2017

  14. Research

    A matched-pair analysis comparing whole-brain radiotherapy with and without a stereotactic boost for intracerebral control and overall survival in patients with one to three cerebral metastases

    Twelve years ago, a randomized trial demonstrated that a radiosurgery boost added to whole-brain radiotherapy (WBRT) improved intracerebral control (IC) in patients with one to three cerebral metastases. Overa...

    Dirk Rades, Stefan Janssen, Amira Bajrovic, Mai Trong Khoa, Theo Veninga and Steven E. Schild

    Radiation Oncology 2017 12:69

    Published on: 24 April 2017

  15. Research

    Long-term follow-up after stereotactic radiosurgery of intracanalicular acoustic neurinoma

    The management of solely intracanalicular acoustic neurinoma (iAN) includes observation, microsurgical resection and radiation therapy. Treatment goals are long-term tumor control, hearing preservation and con...

    Daniel Rueß, Lea Pöhlmann, Stefan Grau, Christina Hamisch, Alexandra Hellerbach, Harald Treuer, Martin Kocher and Maximilian I. Ruge

    Radiation Oncology 2017 12:68

    Published on: 21 April 2017

  16. Research

    Subventricular zones: new key targets for glioblastoma treatment

    We aimed to identify subventricular zone (SVZ)-related prognostic factors of survival and patterns of recurrence among patients with glioblastoma.

    J. Khalifa, F. Tensaouti, A. Lusque, B. Plas, J.-A. Lotterie, A. Benouaich-Amiel, E. Uro-Coste, V. Lubrano and E. Cohen-Jonathan Moyal

    Radiation Oncology 2017 12:67

    Published on: 20 April 2017

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