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  1. Research

    Clinical outcomes of gastrointestinal brain metastases treated with radiotherapy

    Brain metastases of gastrointestinal origin are a rare occurrence. Radiation therapy (RT) in the form of stereotactic radiosurgery (SRS) or whole brain radiation therapy (WBRT) is an effective established trea...

    Samrat M. Sanghvi, Jonathan W. Lischalk, Ling Cai, Sean Collins, Mani Nair, Brain Collins and Keith Unger

    Radiation Oncology 2017 12:43

    Published on: 28 February 2017

  2. Research

    Real-time in vivo rectal wall dosimetry using MOSkin detectors during linac based stereotactic radiotherapy with rectal displacement

    MOSFET dosimetry is a method that has been used to measure in-vivo doses during brachytherapy treatments and during linac based radiotherapy treatment. Rectal displacement devices (RDDs) allow for safe dose es...

    Kimberley Legge, Peter B. Greer, Daryl J. O’Connor, Lee Wilton, Matthew Richardson, Perry Hunter, Alex Wilfert, Jarad Martin, Anatoly Rosenfeld and Dean Cutajar

    Radiation Oncology 2017 12:41

    Published on: 27 February 2017

  3. Research

    A comparative study of dose distribution of PBT, 3D-CRT and IMRT for pediatric brain tumors

    It was reported that proton beam therapy (PBT) reduced the normal brain dose compared with X-ray therapy for pediatric brain tumors. We considered whether there was not the condition that PBT was more disadvan...

    Daichi Takizawa, Masashi Mizumoto, Tetsuya Yamamoto, Yoshiko Oshiro, Hiroko Fukushima, Takashi Fukushima, Toshiyuki Terunuma, Toshiyuki Okumura, Koji Tsuboi and Hideyuki Sakurai

    Radiation Oncology 2017 12:40

    Published on: 22 February 2017

  4. Research

    Definitive salvage radiation therapy and chemoradiation therapy for lymph node oligo-recurrence of esophageal cancer: a Japanese multi-institutional study of 237 patients

    This study evaluated the treatment results of lymph node (LN) oligo-recurrence in esophageal cancer patients treated with salvage radiotherapy (RT) in a multi-institutional retrospective study.

    Hideomi Yamashita, Keiichi Jingu, Yuzuru Niibe, Kuniaki Katsui, Toshihiko Matsumoto, Tomohiro Nishina and Atsuro Terahara

    Radiation Oncology 2017 12:38

    Published on: 20 February 2017

  5. Research

    Concurrent chemoradiotherapy with conventional fractionated radiotherapy and low-dose daily cisplatin plus weekly docetaxel for T2N0 glottic cancer

    To assess the efficacy of concurrent chemoradiotherapy (CCRT) with daily low-dose cisplatin (CDDP) plus weekly docetaxel (DTX) for patients with T2N0 glottic cancer.

    Jun-ichi Saitoh, Katsuyuki Shirai, Masumi Imaeda, Atsushi Musha, Takanori Abe, Masato Shino, Yukihiro Takayasu, Katsumasa Takahashi, Kazuaki Chikamatsu and Takashi Nakano

    Radiation Oncology 2017 12:39

    Published on: 20 February 2017

  6. Research

    Lung metastases treated with stereotactic body radiotherapy: the RSSearch® patient Registry’s experience

    To report overall survival and local control for patients identified in the RSSearch® Patient Registry with metastatic cancer to the lung treated with SBRT.

    Anthony Ricco, Joanne Davis, William Rate, Jun Yang, David Perry, John Pablo, David D‘Ambrosio, Sanjeev Sharma, Srinath Sundararaman, James Kolker, Kimberly M. Creach and Rachelle Lanciano

    Radiation Oncology 2017 12:35

    Published on: 1 February 2017

  7. Research

    Is pulmonary artery a dose-limiting organ at risk in non-small cell lung cancer patients treated with definitive radiotherapy?

    Our previous study suggested that some pulmonary artery (PA) dosimetric parameters were associated with mortality in unresectable non-small cell lung cancer (NSCLC) treated with definitive radiotherapy. The pr...

    Jie-Tao Ma, Li Sun, Xin Sun, Zhi-Cheng Xiong, Yang Liu, Shu-Ling Zhang, Le-Tian Huang and Cheng-Bo Han

    Radiation Oncology 2017 12:34

    Published on: 1 February 2017

  8. Research

    Fully automated treatment planning of spinal metastases – A comparison to manual planning of Volumetric Modulated Arc Therapy for conventionally fractionated irradiation

    Planning for Volumetric Modulated Arc Therapy (VMAT) may be time consuming and its use is limited by available staff resources. Automated multicriterial treatment planning can eliminate this bottleneck. We com...

    Daniel Buergy, Abdul Wahab M. Sharfo, Ben J. M. Heijmen, Peter W. J. Voet, Sebastiaan Breedveld, Frederik Wenz, Frank Lohr and Florian Stieler

    Radiation Oncology 2017 12:33

    Published on: 31 January 2017

  9. Research

    Helical tomotherapy of spinal chordomas: French Multicentric, retrospective study of a cohort of 30 cases

    To evaluate the efficacy and toxicity of helical tomotherapy (HT) in the management of spine chordomas when proton therapy is unavailable or non-feasible.

    Maxime Bobin, Christina Zacharatou, Paul Sargos, Véronique Brouste, Albert Lisbona, Marc-André Mahé, Georges Noël, Amandine Halley, Loïc Feuvret, Louis Gras, Stéphanie Hoppe, Bénédicte Henriques de Figueiredo and Guy Kantor

    Radiation Oncology 2017 12:32

    Published on: 31 January 2017

  10. Research

    Helical TomoTherapy for locally advanced or recurrent breast cancer

    We report our experience of using helical tomotherapy (HT) to treat large and irregular shaped loco-regional advanced breast cancer target volumes embracing various organs at risk.

    M. N. Duma, C. Heinrich, C. Schönknecht, B. Chizzali, M. Mayinger, M. Devecka, S. Kampfer and S. E. Combs

    Radiation Oncology 2017 12:31

    Published on: 28 January 2017

  11. Short report

    Short report: interim safety results for a phase II trial measuring the integration of stereotactic ablative radiotherapy (SABR) plus surgery for early stage non-small cell lung cancer (MISSILE-NSCLC)

    A phase II trial was launched to evaluate if neoadjuvant stereotactic ablative radiotherapy (SABR) before surgery improves oncologic outcomes in patients with stage I non-small cell lung cancer (NSCLC). We rep...

    David A. Palma, Timothy K. Nguyen, Keith Kwan, Stewart Gaede, Mark Landis, Richard Malthaner, Dalilah Fortin, Alexander V. Louie, Eric Frechette, George B. Rodrigues, Brian Yaremko, Edward Yu, A. Rashid Dar, Ting-Yim Lee, Al Gratton, Andrew Warner…

    Radiation Oncology 2017 12:30

    Published on: 27 January 2017

  12. Review

    Present state and issues in IORT Physics

    Literature was reviewed to assess the physical aspects governing the present and emerging technologies used in intraoperative radiation therapy (IORT). Three major technologies were identified: treatment with ...

    Frank W. Hensley

    Radiation Oncology 2017 12:37

    Published on: 27 January 2017

  13. Review

    A review of substitute CT generation for MRI-only radiation therapy

    Radiotherapy based on magnetic resonance imaging as the sole modality (MRI-only RT) is an area of growing scientific interest due to the increasing use of MRI for both target and normal tissue delineation and ...

    Jens M. Edmund and Tufve Nyholm

    Radiation Oncology 2017 12:28

    Published on: 26 January 2017

  14. Review

    Current controversies in radiotherapy for breast cancer

    Multimodal treatment approaches have substantially improved the outcome of breast cancer patients in the last decades. Radiotherapy is an integral component of multimodal treatment concepts used in curative an...

    David Krug, René Baumann, Wilfried Budach, Jürgen Dunst, Petra Feyer, Rainer Fietkau, Wulf Haase, Wolfgang Harms, Marc D. Piroth, Marie-Luise Sautter-Bihl, Felix Sedlmayer, Rainer Souchon, Frederik Wenz and Rolf Sauer

    Radiation Oncology 2017 12:25

    Published on: 23 January 2017

  15. Research

    Evaluation of a novel sodium borocaptate-containing unnatural amino acid as a boron delivery agent for neutron capture therapy of the F98 rat glioma

    Boron neutron capture therapy (BNCT) is a unique particle radiation therapy based on the nuclear capture reactions in boron-10. We developed a novel boron-10 containing sodium borocaptate (BSH) derivative, 1-a...

    Gen Futamura, Shinji Kawabata, Naosuke Nonoguchi, Ryo Hiramatsu, Taichiro Toho, Hiroki Tanaka, Shin-Ichiro Masunaga, Yoshihide Hattori, Mitsunori Kirihata, Koji Ono, Toshihiko Kuroiwa and Shin-Ichi Miyatake

    Radiation Oncology 2017 12:26

    Published on: 23 January 2017

  16. Review

    Intraoperative radiotherapy (IORT) as boost in breast cancer

    The term IORT (intraoperative radiotherapy) is currently used for various techniques that show huge differences in dose delivery and coverage of the tissue at risk. The largest evidence for boost IORT precedin...

    Felix Sedlmayer, Roland Reitsamer, Frederik Wenz, Elena Sperk, Christoph Fussl, Julia Kaiser, Ingrid Ziegler, Franz Zehentmayr, Heinz Deutschmann, Peter Kopp and Gerd Fastner

    Radiation Oncology 2017 12:23

    Published on: 19 January 2017

  17. Review

    Intraoperative radiation therapy (IORT) in pancreatic cancer

    Despite the important improvements made in the fields of surgery, chemotherapy and radiation therapy, pancreatic cancer remains one of the most lethal malignancies. Improved outcomes with novel chemotherapy re...

    Robert Krempien and Falk Roeder

    Radiation Oncology 2017 12:8

    Published on: 19 January 2017

  18. Review

    Intraoperative radiotherapy in gynaecological and genito-urinary malignancies: focus on endometrial, cervical, renal, bladder and prostate cancers

    Intraoperative radiotherapy (IORT) refers to the delivery of a single radiation dose to a limited volume of tissue during a surgical procedure. A literature review was performed to analyze the role of IORT in ...

    Marco Krengli, Carla Pisani, Letizia Deantonio, Daniela Surico, Alessandro Volpe, Nicola Surico and Carlo Terrone

    Radiation Oncology 2017 12:18

    Published on: 19 January 2017

  19. Review

    Biology of high single doses of IORT: RBE, 5 R’s, and other biological aspects

    Intraoperative radiotherapy differs from conventional, fractionated radiotherapy in several aspects that may influence its biological effect. The radiation quality influences the relative biologic effectivenes...

    Carsten Herskind, Lin Ma, Qi Liu, Bo Zhang, Frank Schneider, Marlon R. Veldwijk and Frederik Wenz

    Radiation Oncology 2017 12:24

    Published on: 19 January 2017

  20. Review

    Intraoperative radiation therapy (IORT) in soft-tissue sarcoma

    Soft-tissue sarcoma (STS) represent a rare tumor entity, accounting for less than 1% of adult malignancies. The cornerstone of curative intent treatment is surgery with free margins, although the extent of the...

    Falk Roeder and Robert Krempien

    Radiation Oncology 2017 12:20

    Published on: 19 January 2017

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